I haven't seen the stuff from Home Depot, but I've looked at the tool chests from Harbor Freight, and I really liked their US General brand. If I wasn't a renter and had to face the eventual necessity of moving the damn thing, I'd probably invest in one of those units. I imagine once I get to to where I'm going after the next move, I'll pick up one of their storage systems.
Check out their Icon brand tool chests if you're near a Harbor Freight store. They're outside of my price range, but they're a solid well built unit. Their whole Icon line of tools is pretty nice, to be honest. Harbor Freight definitely has some diamonds mixed in with the junk.
And since FennellG made the suggestion, here's my tool box:
I don't have the room in my garage for one of those nice tool chests, so I had to make my own rolling tool box so it would fit into a small corner by the stairs. Here in the land of hurricanes you gotta be able to get both cars and a motorcycle into the garage to protect them from falling pine trees, so there isn't a ton of room left over. I bought a couple of Craftsman tool boxes on sale and built a cart out of a Harbor Freight furniture dolly and some 2x4's. Not as nice as a dedicated system, but good enough for the moment. Plus, if I have to take my tools somewhere else, it's easy to load the tool boxes into a car trunk. It'll do until I have my hopefully final move.
On a related note, if you ever want to repaint a Craftsman tool box, Rustoleum Apple Red is just about a dead on match for Craftsman red.